Butofilolol

Butofilolol
IUPAC ime
	(RS)-1-[2-[3-(tert-butilamino)-2-hidroksipropoksi]-5-fluorofenil]butan-1-on
Identifikatori
CAS broj	64552-17-6
ATC kod	none
PubChem	CID 68838
ChemSpider	62071
UNII	4AZC6Y5A8G
ChEMBL	CHEMBL157443
Sinonimi	CM-6805
Hemijski podaci
Formula	C17H26FNO3
Molarna masa	311,392 g/mol
	SMILES Fc1ccc(OCC(O)CNC(C)(C)C)c(c1)C(=O)CCC; ;
	InChI InChI=1S/C17H26FNO3/c1-5-6-15(21)14-9-12(18)7-8-16(14)22-11-13(20)10-19-17(2,3)4/h7-9,13,19-20H,5-6,10-11H2,1-4H3 ; Key:NMBNQRJDEPOXCP-UHFFFAOYSA-N ;

Butofilolol (Cafide) je beta-blokator koji potencijalno može naći primenu u tretmanu primarne hipertenzije (visokog krvnog pritiska).^[1]^[2] Ovaj lek nije plasiran na tržište.

Reference

^ Houin, G; Barre, J; Jeanniot, JP; Ledudal, P; Cautreels, W; Tillement, JP (1984). „Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man”. International journal of clinical pharmacology research. 4 (3): 175—83. PMID 6149195.
^ Toussain, P; Gay, G; Debry, G (1983). „Long-term hypotensive treatment by butofilolol”. Annales de cardiologie et d'angeiologie. 32 (4): 277—83. PMID 6412614.

Spoljašnje veze

[1] Houin, G; Barre, J; Jeanniot, JP; Ledudal, P; Cautreels, W; Tillement, JP (1984). „Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man”. International journal of clinical pharmacology research. 4 (3): 175—83. PMID 6149195.

[2] Toussain, P; Gay, G; Debry, G (1983). „Long-term hypotensive treatment by butofilolol”. Annales de cardiologie et d'angeiologie. 32 (4): 277—83. PMID 6412614.

[1]

[2]

IUPAC ime

(RS)-1-[2-[3-(tert-butilamino)-2-hidroksipropoksi]-5-fluorofenil]butan-1-on
Identifikatori
CAS broj	64552-17-6^Y
ATC kod	none
PubChem	CID 68838
ChemSpider	62071^Y
UNII	4AZC6Y5A8G^Y
ChEMBL	CHEMBL157443^Y
Sinonimi	CM-6805
Hemijski podaci
Formula	C₁₇H₂₆FNO₃
Molarna masa	311,392 g/mol
SMILES Fc1ccc(OCC(O)CNC(C)(C)C)c(c1)C(=O)CCC
InChI InChI=1S/C17H26FNO3/c1-5-6-15(21)14-9-12(18)7-8-16(14)22-11-13(20)10-19-17(2,3)4/h7-9,13,19-20H,5-6,10-11H2,1-4H3^Y Key:NMBNQRJDEPOXCP-UHFFFAOYSA-N^Y