Dinoksilin
Dinoksilin je sintetičko jedinjenje koje je razvijeno za primenu u naučnim istraživanjima. Dinoksilin deluje kao potentan pun agonist na svih pet podtipova dopaminskog receptora.[1][2][3]
 | |
| IUPAC ime | |
|---|---|
8,9-dihidroksi-1,2,3,11b-tetrahidrochromeno[4,3,2,-de]isoquinoline | |
| Identifikatori | |
| ATC kod | none |
| PubChem | CID 9819126 |
| Hemijski podaci | |
| Formula | C15H13NO3 |
| Molarna masa | 255,268 |
| |
Reference уреди
- ^ Grubbs RA, Lewis MM, Owens-Vance C, Gay EA, Jassen AK, Mailman RB, Nichols DE (2004). „8,9-dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline (dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms”. Bioorganic & Medicinal Chemistry. 12 (6): 1403—12. PMID 15018913. doi:10.1016/j.bmc.2004.01.008.
- ^ Ryman-Rasmussen JP, Nichols DE, Mailman RB (2005). „Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists”. Molecular Pharmacology. 68 (4): 1039—48. PMID 15985612. doi:10.1124/mol.105.012153.
- ^ Zhang J, Xiong B, Zhen X, Zhang A (2009). „Dopamine D1 receptor ligands: where are we now and where are we going”. Medicinal Research Reviews. 29 (2): 272—94. PMID 18642350. doi:10.1002/med.20130.
