Википедија

GV-196,771

GV-196,771 je antagonist NMDA receptora.[3]

GV-196,771
1H-Indole-2-carboxylic acid, 4,6-dichloro-3-((2-oxo-1-phenyl-3-pyrrolidinylidene)methyl)-, (E)-
Nazivi
Preferisani IUPAC naziv
4,6-dihloro-3-[(E)-(2-okso-1-fenilpirolidin-3-iliden)metil]-1H-indol-2-karboksilna kiselina
Drugi nazivi
  • 166974-22-7
  • GV-196771
  • 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-((2-oxo-1-phenyl-3-pyrrolidinylidene)methyl)-, (E)-
  • 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-((E)-(2-oxo-1-phenyl-3-pyrrolidinylidene)methyl)-
  • GW-196771
Identifikacija
3D model (Jmol)
  • C1CN(C(=O)C1=CC2=C(NC3=C2C(=CC(=C3)Cl)Cl)C(=O)O)C4=CC=CC=C4
Svojstva
C20H14Cl2N2O3
Molarna masa 401,24 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Reference infokutije

Reference

уреди
  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ M S Wallace; M C Rowbotham; N P Katz; R H Dworkin; R M Dotson; B S Galer; R L Rauck; M M Backonja; S N Quessy; P D Meisner (2002-12-10). „A randomized, double-blind, placebo-controlled trial of a glycine antagonist in neuropathic pain”. Neurology. 59 (11): 1694—700. doi:10.1212/01.wnl.0000036273.98213.34. 
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