Indekainid

Indekainid
IUPAC ime
	93-[(propan-2-il)amino]propil9H-fluoren-9-karboksamid
Klinički podaci
Drugs.com	Monografija
Identifikatori
CAS broj	74517-78-5
ATC kod	None
PubChem	CID 52195
DrugBank	DB00192
ChemSpider	47194
Hemijski podaci
Formula	C20H24N2O
Molarna masa	308.4174
	SMILES CC(C)NCCCC1(C(N)=O)C2=CC=CC=C2C2=CC=CC=C12; ;
	InChI InChI=1S/C20H24N2O/c1-14(2)22-13-7-12-20(19(21)23)17-10-5-3-8-15(17)16-9-4-6-11-18(16)20/h3-6,8-11,14,22H,7,12-13H2,1-2H3,(H2,21,23) ; Key:UCEWGESNIULAGX-UHFFFAOYSA-N ;
Fizički podaci
Tačka topljenja	94—95 °C (201—203 °F)

Indekainid je retko korišteni antidisritmik. Indekainid deluje kao lokalni anestetik i pripada grupi antiaritmičkih agenasa koji stabilizuju membrane. On ima elektrofiziološko dejstvo karakteristično za IC klasu antiaritmika.^[1]^[2]^[3]

Reference уреди

^ Giardina EV, Saroff AL, Schneider M: Effect of indecainide in patients with left ventricular dysfunction. Clin Pharmacol Ther. 1990 Nov;48(5):582-9. PMID 2225716
^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMID 21059682.
^ Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (Nucleic Acids Res) (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. 36 (Database issue): D901—6. PMID 18048412.

Spoljašnje veze уреди

Indecainide

Molimo Vas, obratite pažnju na važno upozorenje
u vezi sa temama iz oblasti medicine (zdravlja).

[1] Giardina EV, Saroff AL, Schneider M: Effect of indecainide in patients with left ventricular dysfunction. Clin Pharmacol Ther. 1990 Nov;48(5):582-9. PMID 2225716

[2] Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMID 21059682.

[3] Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (Nucleic Acids Res) (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. 36 (Database issue): D901—6. PMID 18048412.

[1]

[2]

[3]