Korinantin
Korinantin (rauhimbin) je alkaloid prisutan u biljkama vrsta Rauvolfia i Pausinystalia (ranije poznatih kao Corynanthe).[1][2] On je jedan od dva dijastereoizomera johimbina, dok je drugi rauvolscin.[3][4] On je takođe srodan sa ajmalicinom.
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IUPAC ime | |
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metil estar (16β,17α)-17-hidroksi-johimban-16-karboksilne | |
Klinički podaci | |
Način primene | Oralno |
Pravni status | |
Pravni status |
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Identifikatori | |
CAS broj | 483-10-3 ![]() |
ATC kod | none |
PubChem | CID 92766 |
ChemSpider | 83744 |
Hemijski podaci | |
Formula | C21H26N2O3 |
Molarna masa | 354,44 g/mol |
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Reference
уреди- ^ PHILLIPS DD, CHADHA MS (1955). „The alkaloids of Rauwolfia serpentina Benth”. Journal of the American Pharmaceutical Association. American Pharmaceutical Association. 44 (9): 553—67. PMID 13251932.
- ^ „Alkaloids from Rauvolfia canescens; Pharmaceutical Biology - 39(3):Pages 239-240 - Informa Healthcare”. doi:10.1076/phbi.39.3.239.5923.
- ^ Shepperson NB, Duval N, Massingham R, Langer SZ (1981). „Pre- and postsynaptic alpha adrenoceptor selectivity studies with yohimbine and its two diastereoisomers rauwolscine and corynanthine in the anesthetized dog”. The Journal of Pharmacology and Experimental Therapeutics. 219 (2): 540—6. PMID 6270312.
- ^ Doxey JC, Lane AC, Roach AG, Virdee NK (1984). „Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine”. Naunyn-Schmiedeberg's Archives of Pharmacology. 325 (2): 136—44. PMID 6144048.