Ksantozin monofosfat
Ksantozin monofosfat (XMP[3]) je intermedijer u purinskom metabolizmu.[4] On je ribonukleosidni monofosfat. XMP se formira iz inozin monofosfata posredstvom IMP dehidrogenaze, dok se guanozin monofosfat (GMP) formira posredstvom GMP sintaze.
| |
| Nazivi | |
|---|---|
| IUPAC naziv
5'-ksantilinska kiselina
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| Drugi nazivi
ksantinski ribotid,
XMP | |
| Identifikacija | |
| MeSH | Xanthosine+monophosphate |
| Svojstva | |
| C10H13N4O9P | |
| Molarna masa | 364,206 g/mol |
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa). | |
 verifikuj (šta je   ?)
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| Reference infokutije | |
Reference уреди
- ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.
- ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
- ^ Gogia, S.; Balaram, H.; Puranik, M. (2011). „Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.”. Biochemistry. 50 (19): 4184—93. PMID 21486037. doi:10.1021/bi102039b.
- ^ McMurry 2007, стр. 1007
Literatura уреди
- McMurry, John (2007). Organic chemistry: a biological approach. Cengage Learning. стр. 1007—. ISBN 978-0-495-01525-3. Приступљено 26. 3. 2012.
- Sigel, H; Operschall, BP; Griesser, R (2009). „Xanthosine 5'-monophosphate (XMP). Acid-base and metal ion-binding properties of a chameleon-like nucleotide”. Chemical Society reviews. 38 (8): 2465—94. PMID 19623361. doi:10.1039/b902181g.
- Egli, M; Pallan, PS (2010). „Crystallographic studies of chemically modified nucleic acids: A backward glance”. Chemistry & Biodiversity. 7 (1): 60—89. PMC 2905155
. PMID 20087997. doi:10.1002/cbdv.200900177.
