VU-71 je agonist glutamatnog receptora.[3][4]

VU-71
N-[2,4-di(fenil)pirazol-3-il]-4-nitrobenzamid
Nazivi
IUPAC naziv
N-[2,4-di(fenil)pirazol-3-il]-4-nitrobenzamid
Drugi nazivi
  • VU 71
  • CHEMBL377636
  • VU71
  • GTPL6207
  • BDBM50187618
Identifikacija
3D model (Jmol)
  • C1=CC=C(C=C1)C2=C(N(N=C2)C3=CC=CC=C3)NC(=O)C4=CC=C(C=C4)[N+](=O)[O-]
Svojstva
C22H16N4O3
Molarna masa 384,40 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Reference infokutije

Reference уреди

  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ Kamondanai Hemstapat; Tomas de Paulis; Yelin Chen; Ashley E Brady; Vandana K Grover; David Alagille; Gilles D Tamagnan; P Jeffrey Conn (2006). „A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators”. Mol Pharmacol. 70 (2): 616—26. doi:10.1124/mol.105.021857. 
  4. ^ D. E. Jane; H. W. Tse; D. A. Skifter; J. M. Christie; D. T. Monaghan. Pharmacology of Ionic Channel Function: Activators and Inhibitors. Glutamate Receptor Ion Channels: Activators and Inhibitors. Pharmacology of Ionic Channel Function: Activators and Inhibitors. Springer. стр. 415—478.