(6-4)DNK fotolijaza
(6-4)DNK fotolijaza (EC 4.1.99.13, DNK fotolijaza, H64PRH, NF-10, phr (6-4), PL-(6-4), OtCPF1, (6-4) PHR, At64PHR) je enzim sa sistematskim imenom (6-4) fotoprodukt pirimidin-lijaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (6-4)DNK fotolijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.99.13 | ||||||||
| CAS broj | 37290-70-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (6-4) fotoprodukt (u DNK) 2 pirimidinski ostaci (u DNK)
Ovaj enzim je flavoprotein (FAD).
Reference
uredi- ^ Hitomi, K., DiTacchio, L., Arvai, A.S., Yamamoto, J., Kim, S.T., Todo, T., Tainer, J.A., Iwai, S., Panda, S. and Getzoff, E.D. (2009). „Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes”. Proc. Natl. Acad. Sci. USA. 106: 6962—6967. PMID 19359474.
- ^ Schleicher, E., Hitomi, K., Kay, C.W., Getzoff, E.D., Todo, T. and Weber, S. (2007). „Electron nuclear double resonance differentiates complementary roles for active site histidines in (6-4) photolyase”. J. Biol. Chem. 282: 4738—4747. PMID 17164245.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
uredi- (6-4)DNA+photolyase на US National Library of Medicine Medical Subject Headings (MeSH)