Alfa-Metilhistamin
α-Metilhistamin je histaminski agonist koji je selektivan za histaminski H3 receptor. On uzrokuje snižavanje krvnog pritiska i usporavanje brzine otkucaja srca u životinjskim modelima.[4]
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Nazivi | |
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IUPAC naziv
1-(3H-Imidazol-4-il)propan-2-amin
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Sistemski IUPAC naziv
1-(1H-Imidazol-4-il)propan-2-amin[1] | |
Identifikacija | |
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3D model (Jmol)
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ChEBI | |
ChemSpider | |
MeSH | Alpha-methylhistamine |
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Svojstva | |
C6H11N3 | |
Molarna masa | 125,18 g·mol−1 |
log P | -0,346 |
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa). | |
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Reference infokutije | |
Reference
uredi- ^ Compound Name and Classification[мртва веза]
- ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.
- ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
- ^ McLeod, RL; Gertner, SB; Hey, JA (1993). „Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs”. Br J Pharmacol. 110 (2): 553—558. PMC 2175947 . PMID 7902173.