Aspartat kinaza
(преусмерено са Aspartokinaza)
Aspartat kinaza (EC 2.7.2.4, aspartokinaza, AK, beta-aspartokinaza, aspartinska kinaza) je enzim sa sistematskim imenom ATP:L-aspartat 4-fosfotransferaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Aspartat kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.2.4 | ||||||||
| CAS broj | 9012-50-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Enzim iz Escherichia coli je multifunkcionalni protein, koji takođe katalizuje reakciju EC 1.1.1.3, homoserin dehidrogenaze.
Reference
уреди- ^ Black, S. (1962). „Conversion of aspartic acid to homoserine”. Methods Enzymol. 5: 820—827.
- ^ Paulus, H. & Gray, E. (1967). „Multivalent feedback inhibition of aspartokinase in Bacillus polymyxa. I. Kinetic studies”. J. Biol. Chem. 242: 4980—4986. PMID 6058940.
- ^ Starnes, W.L., Munk, P., Maul, S.B., Cunningham, G.N., Cox, D.J. and Shive, W. (1972). „Threonine-sensitive aspartokinase-homoserine dehydrogenase complex, amino acid composition, molecular weight, and subunit composition of the complex”. Biochemistry. 11: 677—687. PMID 4551091.
- ^ Véron, M., Falcoz-Kelly, F. and Cohen, G.N. (1972). „The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. The two catalytic activities are carried by two independent regions of the polypeptide chain”. Eur. J. Biochem. 28: 520—527. PMID 4562990.
- ^ Chassagnole, C., Rais, B., Quentin, E., Fell, D. A. and Mazat, J.-P. (2001). „An integrated study of threonine-pathway enzyme kinetics in Escherichia coli”. Biochem. J. 356: 415—423.
- ^ Curien, G., Ravanel, S., Robert, M. and Dumas, R. (2005). „Identification of six novel allosteric effectors of Arabidopsis thaliana aspartate kinase-homoserine dehydrogenase isoforms”. J. Biol. Chem. 280: 41178—41183.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Aspartate+kinase на US National Library of Medicine Medical Subject Headings (MeSH)
