(S,S)-butandiol dehidrogenaza
(S,S)-butandiol dehidrogenaza (EC 1.1.1.76, L-butandiol dehidrogenaza, L-BDH, L(+)-2,3-butandiol dehidrogenaza (formira L-acetoin), (S)-acetoin reduktaza (formira (S,S)-butan-2,3-diol)) je enzim sa sistematskim imenom (S,S)-butan-2,3-diol:NAD+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (S,S)-butandiol dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.76 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (2S,3S)-butan-2,3-diol + NAD+ (S)-acetoin + NADH + H+
Ovaj enzim katalizuje reverzibilnu redukciju (S)-acetoina do (S,S)-butan-2,3-diol. On takođe može da katalizuje ireverzibilnu redukciju diacetila do (S)-acetoina.
Reference уреди
- ^ Taylor, M.B. & Juni, E. (1960). „Stereoisomeric specificities of 2,3-butanediol dehydrogenase”. Biochim. Biophys. Acta. 39: 448—457. PMID 13837186.
- ^ Carballo, J., Martin, R., Bernardo, A. and Gonzalez, J. (1991). „Purification, characterization and some properties of diacetyl(acetoin) reductase from Enterobacter aerogenes”. Eur. J. Biochem. 198: 327—332. PMID 2040298.
- ^ Takusagawa, Y., Otagiri, M., Ui, S., Ohtsuki, T., Mimura, A., Ohkuma, M. and Kudo, T. (2001). „Purification and characterization of L-2,3-butanediol dehydrogenase of Brevibacterium saccharolyticum C-1012 expressed in Escherichia coli”. Biosci. Biotechnol. Biochem. 65: 1876—1878. PMID 11577733.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- (S,S)-butanediol+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
