(2Z,6E)-farnezil difosfat sintaza
(2Z,6E)-farnezil difosfat sintaza (EC 2.5.1.68, (Z)-farnezil difosfat sintaza, Z-farnezil difosfat sintaza) je enzim sa sistematskim imenom geranil-difosfat:izopentenil-difosfat geranilcistransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (2Z,6E)-farnezil difosfat sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.68 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- geranil difosfat + izopentenil difosfat difosfat + (2Z,6E)-farnezil difosfat
Za dejstvo ovog enzima je neophodan Mg2+ ili Mn2+.
Reference уреди
- ^ Schulbach, M.C., Mahapatra, S., Macchia, M., Barontini, S., Papi, C., Minutolo, F., Bertini, S., Brennan, P.J. and Crick, D.C. (2001). „Purification, enzymatic characterization, and inhibition of the Z-farnesyl diphosphate synthase from Mycobacterium tuberculosis”. J. Biol. Chem. 276: 11624—11630. PMID 11152452.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- (2Z,6E)-farnesyl+diphosphate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
