(4S)-beta-felandrenska sintaza (geranil-difosfat-ciklizacija)
(4S)-beta-felandrenska sintaza (geranil-difosfat-ciklizacija) (EC 4.2.3.52, felandrenska sintaza, (-)-beta-phelandrenska sintaza, (-)-(4S)-beta-felandrenska sintaza) je enzim sa sistematskim imenom geranil-difosfat difosfat-lijaza (ciklizacija, formira (4S)-beta-felandren).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (4S)-beta-felandrenska sintaza (geranil-difosfat-ciklizacija) | |||||||||
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| Identifikatori | |||||||||
| EC broj | 4.2.3.52 | ||||||||
| CAS broj | 137010-34-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- geranil difosfat (4S)-beta-felandren + difosfat
Za dejstvo ovog enzima je neophodan jon Mn2+.
Reference уреди
- ^ Savage, T.J., Hatch, M.W. and Croteau, R. (1994). „Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase”. J. Biol. Chem. 269: 4012—4020. PMID 8307957.
- ^ Bohlmann, J., Phillips, M., Ramachandiran, V., Katoh, S. and Croteau, R. (1999). „cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis)”. Arch. Biochem. Biophys. 368: 232—243. PMID 10441373.
- ^ Wagschal, K., Savage, T.J. and Croteau, R. (1991). „Isotopically sensitive branching as a tool for evaluating multiple product formation by monoterpene cyclases”. Tetrahedron. 31: 5933—5944.
- ^ LaFever, R.E. & Croteau, R. (1993). „Hydride shifts in the biosynthesis of the p-menthane monoterpenes α-terpinene, γ-terpinene, and β-phellandrene”. Arch. Biochem. Biophys. 301: 361—366. PMID 8460944.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- (4S)-beta-phellandrene+synthase+(geranyl-diphosphate-cyclizing) на US National Library of Medicine Medical Subject Headings (MeSH)
