(R)-6-hidroksinikotin oksidaza
(R)-6-hidroksinikotin oksidaza (EC 1.5.3.6, D-6-hidroksinikotinska oksidaza, 6-hidroksi-D-nikotinska oksidaza) je enzim sa sistematskim imenom (R)-6-hidroksinikotin:kiseonik oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (R)-6-hidroksinikotin oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.3.6 | ||||||||
| CAS broj | 37233-46-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (R)-6-hidroksinikotin + H2O + O2 1-(6-hidroksipiridin-3-il)-4-(metilamino)butan-1-on + H2O2
Ovaj enzim je flavoprotein (FAD).
Reference уреди
- ^ Brühmüller, M., Möhler, H.K. and Decker, K. (1972). „Covalently bound flavin in D-6-hydroxynicotine oxidase from Arthrobacter oxidans. Purification and properties of D-6-hydroxynicotine oxidase”. Eur. J. Biochem. 29: 143—151. PMID 4628374.
- ^ Decker, K. & Bleeg, H. (1965). „Induction and purification of stereospecific nicotine oxidizing enzymes from Arthrobacter oxidans”. Biochim. Biophys. Acta. 105: 313—324. PMID 5849820.
- ^ Koetter, J.W. & Schulz, G.E. (2005). „Crystal structure of 6-hydroxy-D-nicotine oxidase from Arthrobacter nicotinovorans”. J. Mol. Biol. 352: 418—428. PMID 16095622.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- (R)-6-hydroxynicotine+oxidase на US National Library of Medicine Medical Subject Headings (MeSH)
