(d)CMP kinaza
(d)CMP kinaza (EC 2.7.4.25, prokariotska citidilatna kinaza, dezoksicitidilatna kinaza, dCMP kinaza, dezoksicitidinna monofosfokinaza) je enzim sa sistematskim imenom ATP:(d)CMP fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (d)CMP kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.4.25 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Prokariotska citidin monofosfatna kinaza specifično fosforiliše CMP (ili dCMP), koristeći ATP kao preferentni fosforilni donor.
Reference уреди
- ^ Bertrand T, Briozzo P, Assairi L, Ofiteru A, Bucurenci N, Munier-Lehmann H, Golinelli-Pimpaneau B, Barzu O, Gilles AM (2002). „Sugar specificity of bacterial CMP kinases as revealed by crystal structures and mutagenesis of Escherichia coli enzyme”. J. Mol. Biol. 315: 1099—1110. PMID 11827479.
- ^ Thum C, Schneider CZ, Palma MS, Santos DS, Basso LA (2009). „The Rv1712 Locus from Mycobacterium tuberculosis H37Rv codes for a functional CMP kinase that preferentially phosphorylates dCMP”. J. Bacteriol. 191: 2884—2887. PMID 19181797.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- (d)CMP+kinase на US National Library of Medicine Medical Subject Headings (MeSH)
