2,3-Dihidroksibenzoat-serinska ligaza
(преусмерено са 2,3-dihidroksibenzoat-serin ligaza)
2,3-Dihidroksibenzoat-serinska ligaza (EC 6.3.2.14, N-(2,3-dihidroksibenzoil)-serin sintetaza, 2,3-dihidroksibenzoilserin sintetaza, 2,3-dihidroksibenzoat—serin ligaza) je enzim sa sistematskim imenom 2,3-dihidroksibenzoat:L-serin ligaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 2,3-Dihidroksibenzoat-serinska ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.2.14 | ||||||||
| CAS broj | 37318-63-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzimski kompleks katalizuje konverziju molekula koji se formiraju siderofori enterobaktina.
Reference уреди
- ^ Brot, N. & Goodwin, J. (1968). „Regulation of 2,3-dihydroxybenzoylserine synthetase by iron”. J. Biol. Chem. 243: 510—513. PMID 4966114.
- ^ Rusnak, F., Faraci, W.S. and Walsh, C.T. (1989). „Subcloning, expression, and purification of the enterobactin biosynthetic enzyme 2,3-dihydroxybenzoate-AMP ligase: demonstration of enzyme-bound (2,3-dihydroxybenzoyl)adenylate product”. Biochemistry. 28: 6827—6835. PMID 2531000.
- ^ Rusnak, F., Liu, J., Quinn, N., Berchtold, G.A. and Walsh, C.T. (1990). „Subcloning of the enterobactin biosynthetic gene entB: expression, purification, characterization, and substrate specificity of isochorismatase”. Biochemistry. 29: 1425—1435. PMID 2139796.
- ^ Rusnak, F., Sakaitani, M., Drueckhammer, D., Reichert, J. and Walsh, C.T. (1991). „Biosynthesis of the Escherichia coli siderophore enterobactin: sequence of the entF gene, expression and purification of EntF, and analysis of covalent phosphopantetheine”. Biochemistry. 30: 2916—2927. PMID 1826089.
- ^ Gehring, A.M., Mori, I. and Walsh, C.T. (1998). „Reconstitution and characterization of the Escherichia coli enterobactin synthetase from EntB, EntE, and EntF”. Biochemistry. 37: 2648—2659. PMID 9485415.
- ^ Shaw-Reid, C.A., Kelleher, N.L., Losey, H.C., Gehring, A.M., Berg, C. and Walsh, C.T. (1999). „Assembly line enzymology by multimodular nonribosomal peptide synthetases: the thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization”. Chem. Biol. 6: 385—400. PMID 10375542.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Enterobactin+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
