3-Oksokiselina KoA-transferaza
3-oksokiselina KoA-transferaza (EC 2.8.3.5, 3-oksokiselina koenzim A-transferaza, 3-ketokiselina KoA-transferaza, 3-ketokiselina koenzim A transferaza, 3-okso-KoA transferaza, 3-oksokiselina KoA dehidrogenaza, acetoacetat sukcinil-KoA transferaza, acetoacetil koenzim A-sukcinska tioforaza, sukcinil koenzim A-acetoacetil koenzim A-transferaza, sukcinil-KoA transferaza) je enzim sa sistematskim imenom sukcinil-KoA:3-okso-kiselina KoA-transferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 3-oksokiselina KoA-transferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.8.3.5 | ||||||||
| CAS broj | 9027-43-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- sukcinil-KoA + a 3-okso kiselina sukcinat + a 3-oksoacil-KoA
Acetoacetat i u manjoj meri 3-oksopropanoat, 3-oksopentanoat, 3-okso-4-metilpentanoat ili 3-oksoheksanoat mogu da deluju kao akceptori.
Reference
уреди- ^ Hersh, L.B. & Jencks, W.P. (1967). „Coenzyme A transferase. Kinetics and exchange reactions”. J. Biol. Chem. 242: 3468—3480.
- ^ Lynen, F. & Ochoa, S. (1953). „Enzymes of fatty acid metabolism”. Biochim. Biophys. Acta. 12: 299—314. PMID 13115439.
- ^ Menon, G.K.K. & Stern, J.R. (1960). „Enzymic synthesis and metabolism of malonyl coenzyme A and glutaryl coenzyme A”. J. Biol. Chem. 235: 3393—3398. PMID 13769479.
- ^ Stern, J.R., Coon, M.J., del Campillo, A. and Schneider, M.C. (1956). „Enzymes of fatty acid metabolism. IV. Preparation and properties of coenzyme A transferase”. J. Biol. Chem. 221: 15—31. PMID 13345795.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- 3-oxoacid+CoA-transferase на US National Library of Medicine Medical Subject Headings (MeSH)
