4-Kumarat-KoA ligaza

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PMC	članci
PubMed	članci
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4-kumarat-KoA ligaza
4-kumarat-KoA ligaza
Identifikatori
EC broj	6.2.1.12
CAS broj	37332-51-7
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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PMC	članci
PubMed	članci
NCBI	proteini

4-kumarat-KoA ligaza (EC 6.2.1.12, 4-kumaroil-KoA sintetaza, p-kumaroil KoA ligaza, p-kumaril koenzim A sintetaza, p-kumaril-KoA sintetaza, p-kumaril-KoA ligaza, feruloil KoA ligaza, hidroksicinamoil KoA sintetaza, 4-kumarat:koenzim A ligaza, kafeolil koenzim A sintetaza, p-hidroksicinamoil koenzim A sintetaza, feruloil koenzim A sintetaza, sinapoil koenzim A sintetaza, 4-kumaril-KoA sintetaza, hidroksicinamat:KoA ligaza, p-kumaril-KoA ligaza, p-hidroksicinaminska kiselina:KoA ligaza, 4CL) je enzim sa sistematskim imenom 4-kumarat:KoA ligaza (formira AMP).^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + 4-kumarat + KoA

\rightleftharpoons

AMP + difosfat + 4-kumaroil-KoA

Reference

^ Gross, G.G. & Zenk, M.H. (1974). „Isolation and properties of hydroxycinnamate: CoA ligase from lignifying tissue of Forsythia”. Eur. J. Biochem. 42: 453—459. PMID 4364250.
^ Lindl, T., Kreuzaler, F. and Hahlbrock, F. (1973). „Synthesis of p-coumaroyl coenzyme A with a partially purified p-coumarate:CoA ligase from cell suspension cultures of soybean (Glycine max)”. Biochim. Biophys. Acta. 302: 457—464. PMID 4699252.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

4-coumarate---CoA+ligase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Gross, G.G. & Zenk, M.H. (1974). „Isolation and properties of hydroxycinnamate: CoA ligase from lignifying tissue of Forsythia”. Eur. J. Biochem. 42: 453—459. PMID 4364250.

[2] Lindl, T., Kreuzaler, F. and Hahlbrock, F. (1973). „Synthesis of p-coumaroyl coenzyme A with a partially purified p-coumarate:CoA ligase from cell suspension cultures of soybean (Glycine max)”. Biochim. Biophys. Acta. 302: 457—464. PMID 4699252.

[1]

[2]