5,10-metilentetrahidrometanopterin reduktaza
5,10-metilentetrahidrometanopterin reduktaza (EC 1.5.99.11, 5,10-metilintetrahidrometanopterinska ciklohidrolaza, N5,N10-metilintetrahidrometanopterinska reduktaza, metilin-H4MPT reduktaza, koenzim F420-zavisna N5,N10-meteniltetrahidrometanopterinska reduktaza, N5,N10-metilintetrahidrometanopterin:koenzim-F420 oksidoreduktaza) je enzim sa sistematskim imenom 5-metiltetrahidrometanopterin:koenzim-F420 oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 5,10-metilentetrahidrometanopterin reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.99.11 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- 5-metiltetrahidrometanopterin + koenzim F420 5,10-metilintetrahidrometanopterin + redukovani koenzim F420
Ovaj enzim katalizuje intermedijerni korak u metanogenezi iz CO2 i H2 kod bakterija.
Reference
уреди- ^ Ma, K. & Thauer, R.K. (1990). „Purification and properties of N5,N10-methylenetetrahydromethanopterin reductase from Methanobacterium thermoautotrophicum (strain Marburg)”. Eur. J. Biochem. 191: 187—193. PMID 2379499.
- ^ te Brömmelstroet, B.W., Geerts, W.J., Keltjens, J.T., van der Drift, C. and Vogels, G.D. (1991). „Purification and properties of 5,10-methylenetetrahydromethanopterin dehydrogenase and 5,10-methylenetetrahydromethanopterin reductase, two coenzyme F420-dependent enzymes, from Methanosarcina barkeri”. Biochim. Biophys. Acta. 1079: 293—302. PMID 1911853.
- ^ Ma, K. & Thauer, R.K. (1990). „Single step purification of methylenetetrahydromethanopterin reductase from Methanobacterium thermoautotrophicum by specific binding to blue sepharose CL-6B”. FEBS Lett. 268: 59—62. PMID 1696553.
- ^ te Brömmelstroet, B.W., Hensgens, C.M., Keltjens, J.T., van der Drift, C. and Vogels, G.D. (1990). „Purification and properties of 5,10-methylenetetrahydromethanopterin reductase, a coenzyme F420-dependent enzyme, from Methanobacterium thermoautotrophicum strain ΔH*”. J. Biol. Chem. 265: 1852—1857. PMID 2298726.
- ^ te Brömmelstroet, B.W., Hensgens, C.M., Geerts, W.J., Keltjens, J.T., van der Drift, C. and Vogels, G.D. (1990). „Purification and properties of 5,10-methenyltetrahydromethanopterin cyclohydrolase from Methanosarcina barkeri”. J. Bacteriol. 172: 564—571. PMID 2298699.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- 5,10-methylenetetrahydromethanopterin+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
