7-Cijano-7-deazaguaninska sintaza
7-Cijano-7-deazaguaninska sintaza (EC 6.3.4.20, preQ0 sintaza, 7-cijano-7-karbaguanin sintaza, queC (gen)) je enzim sa sistematskim imenom 7-karboksi-7-karbaguanin:amonijak ligaza (formira ADP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 7-Cijano-7-deazaguaninska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.4.20 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ovaj enzim vezuje Zn2+.
Reference уреди
- ^ McCarty, R.M., Somogyi, A., Lin, G., Jacobsen, N.E. and Bandarian, V. (2009). „The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of preQ0 from guanosine 5′-triphosphate in four steps”. Biochemistry. 48: 3847—3852. PMID 19354300.
- ^ Cicmil, N. & Huang, R.H. (2008). „Crystal structure of QueC from Bacillus subtilis: an enzyme involved in preQ1 biosynthesis”. Proteins. 72: 1084—1088. PMID 18491386.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- 7-cyano-7-deazaguanine+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
