A,a-trehaloza fosforilaza (sa zadržavanjem konfiguracije)
A,a-trehaloza fosforilaza (sa zadržavanjem konfiguracije) (EC 2.4.1.231, trehalozna fosforilaza) je enzim sa sistematskim imenom alfa,alfa-trehaloza:fosfat alfa-D-glukoziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| A,a-trehaloza fosforilaza (sa zadržavanjem konfiguracije) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.231 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- alfa,alfa-trehaloza + fosfat alfa-D-glukoza + alfa-D-glukoza 1-fosfat
Za razliku od EC 2.4.1.64, alfa,alfa-trehaloza fosforilaze, ovaj enzim zadržava anomernu konfiguraciju.
Reference уреди
- ^ Eis, C. & Nidetzky, B. (2002). „Substrate-binding recognition and specificity of trehalose phosphorylase from Schizophyllum commune examined in steady-state kinetic studies with deoxy and deoxyfluoro substrate analogues and inhibitors”. Biochem. J. 363: 335—340. PMID 11931662.
- ^ Eis, C., Watkins, M., Prohaska, T. and Nidetzky, B. (2001). „Fungal trehalose phosphorylase: kinetic mechanism, pH-dependence of the reaction and some structural properties of the enzyme from Schizophyllum commune”. Biochem. J. 356: 757—767. PMID 11389683.
- ^ Nidetzky, B. & Eis, C. (2001). „α-Retaining glucosyl transfer catalysed by trehalose phosphorylase from Schizophyllum commune: mechanistic evidence obtained from steady-state kinetic studies with substrate analogues and inhibitors”. Biochem. J. 360: 727—736. PMID 11736665.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Alpha,alpha-trehalose+phosphorylase+(configuration-retaining) на US National Library of Medicine Medical Subject Headings (MeSH)
