Aminodezoksihorizmatna lijaza
Aminodezoksihorizmatna lijaza (EC 4.1.3.38, enzim X, 4-amino-4-dezoksihorizmat lijaza, 4-amino-4-dezoksihorizmat piruvat-lijaza) je enzim sa sistematskim imenom 4-amino-4-dezoksihorizmat piruvat-lijaza (formira 4-aminobenzoat).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Aminodezoksihorizmatna lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.3.38 | ||||||||
| CAS broj | 132264-33-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 4-amino-4-dezoksihorizmat 4-aminobenzoat + piruvat
Ovaj enzim je piridoksal-fosfatni protein.
Reference
уреди- ^ Ye, Q.Z., Liu, J. and Walsh, C.T. (1990). „p-Aminobenzoate synthesis in Escherichia coli: purification and characterization of PabB as aminodeoxychorismate synthase and enzyme X as aminodeoxychorismate lyase”. Proc. Natl. Acad. Sci. USA. 87: 9391—9395. PMID 2251281.
- ^ Green, J.M., Merkel, W.K. and Nichols, B.P. (1992). „Characterization and sequence of Escherichia coli pabC, the gene encoding aminodeoxychorismate lyase, a pyridoxal phosphate-containing enzyme”. J. Bacteriol. 174: 5317—5323. PMID 1644759.
- ^ Nakai, T., Mizutani, H., Miyahara, I., Hirotsu, K., Takeda, S., Jhee, K.H., Yoshimura, T. and Esaki, N. (2000). „Three-dimensional structure of 4-amino-4-deoxychorismate lyase from Escherichia coli”. J. Biochem. 128: 29—38. PMID 10876155.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Aminodeoxychorismate+lyase на US National Library of Medicine Medical Subject Headings (MeSH)
