Aminopeptidaza Y
Aminopeptidaza Y (EC 3.4.11.15, aminopeptidaza Co, aminopeptidaza (kobaltom aktivirana), lizilna aminopeptidaza) je enzim'.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Aminopeptidaza Y | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Lizilna aminopeptidaza dodekamer, Pyrococcus furiosus | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.11.15 | ||||||||
| CAS broj | 114796-97-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Preferentno odvajanje N-terminalnog lizina
Za dejstvo ovog enzima je neophodan Co2+. Inhibiraju ga Zn2+ i Mn2+.
Reference уреди
- ^ Achstetter, T., Ehmann, C. and Wolf, D.H. (1982). „Aminopeptidase Co, a new yeast peptidase”. Biochem. Biophys. Res. Commun. 109: 341—347. PMID 6758786.
- ^ Yasuhara, T., Nakai, T. and Ohashi, A. (1994). „Aminopeptidase Y, a new aminopeptidase from Saccharomyces cerevisiae. Purification, properties, localization, and processing by protease B”. J. Biol. Chem. 269: 13644—13650. PMID 8175799.
- ^ Nishizawa, M., Yasuhara, T., Nakai, T., Fujiki, Y. and Ohashi, A. (1994). „Molecular cloning of the aminopeptidase Y gene of Saccharomyces cerevisiae. Sequence analysis and gene disruption of a new aminopeptidase”. J. Biol. Chem. 269: 13651—13655. PMID 8175800.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Aminopeptidase+Y на US National Library of Medicine Medical Subject Headings (MeSH)
