Antranilatna sintaza
Antranilatna sintaza (EC 4.1.3.27, antranilatna sintetaza, horizmatna piruvat-lijaza (amino prihvatajuća), TrpE) je enzim sa sistematskim imenom horizmat piruvat-lijaza (amino prihvatajuća; formira antranilat).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Antranilatna sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.3.27 | ||||||||
| CAS broj | 9031-59-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
U pojedinim organizmima ovaj enzim je deo multifunkcionalnog proteina.
Reference уреди
- ^ Baker, T. & Crawford, I.P. (1966). „Anthranilate synthetase. Partial purification and some kinetic studies on the enzyme from Escherichia coli”. J. Biol. Chem. 241: 5577—5584. PMID 5333199.
- ^ Creighton, T.E. & Yanofsky, C. (1970). „Chorismate to tryptophan (Escherichia coli) - anthranilate synthetase, PR transferase, PRA isomerase, InGP synthetase, tryptophan synthetase”. Methods Enzymol. 17A: 365—380.
- ^ Hütter, R., Niederberger, P. and DeMoss, J.A. (1986). „Tryptophan synthetic genes in eukaryotic microorganisms”. Annu. Rev. Microbiol. 40: 55—77. PMID 3535653.
- ^ Ito, J. & Yanofsky, C. (1969). „Anthranilate synthetase, an enzyme specified by the tryptophan operon of Escherichia coli: Comparative studies on the complex and the subunits”. J. Bacteriol. 97: 734—742. PMID 4886290.
- ^ Zalkin, H. & Kling, D. (1968). „Anthranilate synthetase. Purification and properties of component I from Salmonella typhimurium”. Biochemistry. 7: 3566—3573. PMID 4878701.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Anthranilate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
