Azobenzen reduktaza
Azobenzen reduktaza (EC 1.7.1.6, NC-reduktaza, NAD(P)H:1-(4'-sulfofenilazo)-2-naftolna oksidoreduktaza, oranž I azoreduktaza, azo reduktaza, azoreduktaza, nikotinamid adenin dinukleotid (fosfat) azoreduktaza, NADPH2-zavisna azoreduktaza, dimetilaminobenzenska reduktaza, p-dimetilaminoazobenzenska azoreduktaza, dibromopropilaminofenilazobenzoinska azoreduktaza, N,N-dimetil-4-fenilazoanilin azoreduktaza, p-aminoazobenzenska reduktaza, metil crvena azoreduktaza, NADPH2:4-(dimetilamino)azobenzenska oksidoreduktaza) je enzim sa sistematskim imenom N,N-dimetil-1,4-fenilendiamin, anilin:NADP+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Azobenzen reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.7.1.6 | ||||||||
| CAS broj | 9029-31-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- N,N-dimetil-1,4-fenilenediamin + anilin + 2 NADP+ 4-(dimetilamino)azobenzen + 2 NADPH + 2 H+
Reakcija se odvija u reverznom smeru.
Reference
уреди- ^ Mueller, G.C. & Miller, J.A. (1949). „The reductive cleavage of 4-dimethylaminoazobenzene by rat liver: the intracellular distribution of the enzyme system and its requirements for triphosphopyridine nucleotide”. J. Biol. Chem. 180: 1125—1136.
- ^ Suzuki, Y., Yoda, T., Ruhul, A. and Sugiura, W. (2001). „Molecular cloning and characterization of the gene coding for azoreductase from Bacillus sp. OY1-2 isolated from soil”. J. Biol. Chem. 276: 9059—9065. PMID 11134015.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Azobenzene+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
