Berberin reduktaza
Berberin reduktaza (EC 1.5.1.31, (R)-kanadinska sintaza) je enzim sa sistematskim imenom (R)-tetrahidroberberin:NADP+ oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Berberin reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.1.31 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (R)-kanadin + 2 NADP+ berberin + 2 NADPH + H+
Ovaj enzim učestvuje u alkaloidnoj biosintezi kod Corydalis cava.
Reference
уреди- ^ Bauer, W. & Zenk, M.H. (1991). „Formation of (R)-configurated tetrahydroprotoberberine alkaloids in vivo and in vitro”. Tetrahedron Lett. 32: 487—490.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Berberine+reductase на US National Library of Medicine Medical Subject Headings (MeSH)
