Cis-abienolna sintaza
Cis-abienolna sintaza (EC 4.2.3.140, Z-abienolna sintaza, CAS, ABS) je enzim sa sistematskim imenom (13E)-8alfa-hidroksilabd-13-en-15-il-difosfat-lijaza (formira cis-abienol ).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Cis-abienolna sintaza | |||||||||
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Identifikatori | |||||||||
EC broj | 4.2.3.140 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- (13E)-8alfa-hidroksilabD-13-en-15-il difosfat cis-abienol + difosfat
Ovaj enzim je izolovan iz biljke Abies balsamea (балзамаста јела).
Reference
уреди- ^ Zerbe, P., Chiang, A., Yuen, M., Hamberger, B., Hamberger, B., Draper, J.A., Britton, R. and Bohlmann, J. (2012). „Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production”. J. Biol. Chem. 287: 12121—12131. PMID 22337889.
- ^ Sallaud, C., Giacalone, C., Topfer, R., Goepfert, S., Bakaher, N., Rosti, S. and Tissier, A. (2012). „Characterization of two genes for the biosynthesis of the labdane diterpene Z-abienol in tobacco (Nicotiana tabacum) glandular trichomes”. Plant J. 72: 1—17. PMID 22672125.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Cis-abienol+synthase на US National Library of Medicine Medical Subject Headings (MeSH)