DCMP deaminaza
DCMP deaminaza (EC 3.5.4.12, dezoksicitidilatna deaminaza, dezoksi-CMP-deaminaza, dezoksicitidilatna aminohidrolaza, dezoksicitidin monofosfatna deaminaza, dezoksicitidin-5'-fosfatna deaminaza, dezoksicitidin-5'-monofosfatna aminohidrolaza) je enzim sa sistematskim imenom dCMP aminohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| DCMP deaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 DCMP deaminaza hexamer, Cyanophage | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.5.4.12 | ||||||||
| CAS broj | 9026-92-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- dCMP + H2O dUMP + NH3
Ovaj enzim takođe deluje na pojedina 5-supstituisana dCMP jedinjenja.
Reference уреди
- ^ Scarano, E. (1960). „The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5′-phosphate and of 5-methyldeoxycytidine 5-methyldeoxycytidine 5′-phosphate”. J. Biol. Chem. 235: 706—713. PMID 14442222.
- ^ Scarano, E., Bonaduce, L. and de Petrocellis, B. (1960). „The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. II. Purification and properties of a 6-aminopyrimidine deoxyribonucleoside 5′-phosphate deaminase from unfertilized eggs of sea urchin”. J. Biol. Chem. 235: 3556—3561. PMID 13747062.
- ^ Sergott, R.C., Debeer, L.J. and Bessman, M.J. (1971). „On the regulation of a bacterial deoxycytidylate deaminase”. J. Biol. Chem. 246: 7755—7758. PMID 5002683.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- DCMP+deaminase на US National Library of Medicine Medical Subject Headings (MeSH)
