Mevaldat reduktaza (NADPH)
(преусмерено са EC 1.1.1.33)
Mevaldat reduktaza (NADPH) (EC 1.1.1.33, mevaldat (redukovani nikotinamid adenin dinukleotid fosfat) reduktaza) je enzim sa sistematskim imenom (R)-mevalonat:NADP+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Mevaldat reduktaza (NADPH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.33 | ||||||||
| CAS broj | 9028-34-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- (R)-mevalonat + NADP+ mevaldat + NADPH + H+
Dva supstrata ovog enzima su (R)-mevalonat i NADP+, dok su njegova 3 produkta: mevaldat, NADPH, i H+.
Reference уреди
- ^ Coon, M.J., Kupiecki, F.P., Dekker, E.E., Schlesinger, M.J. and del Campillo, A. (1959). „The enzymic synthesis of branched-chain acids”. Ур.: Wolstenholme, G.E.W. and O'Connor, M. CIBA Symposium on the Biosynthesis of Terpenes and Sterols. London: CIBA Symposium on the Biosynthesis of Terpenes and Sterols. стр. 62—74.
- ^ von Wartburg, J.P. & Wermoth, B. (1980). „Aldehyde reductase”. Ур.: Jakoby, W.B. Enzymatic Basis of Detoxication. 1. New York: Academic Press. стр. 249—260.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Mevaldate+reductase+(NADPH) на US National Library of Medicine Medical Subject Headings (MeSH)
