2-oksopropil-KoM reduktaza (karboksilacija)
(преусмерено са EC 1.8.1.5)
2-oksopropil-KoM reduktaza (karboksilacija) (EC 1.8.1.5, NADPH:2-(2-ketopropiltio)etansulfonat oksidoreduktaza/karboksilaza, NADPH:2-ketopropil-koenzim M oksidoreduktaza/karboksilaza) je enzim sa sistematskim imenom 2-merkaptoetansulfonat,acetoacetat:NADP+ oksidoreduktaza (dekarboksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 2-oksopropil-KoM reduktaza (karboksilacija) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.1.5 | ||||||||
| CAS broj | 244301-63-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2-merkaptoetansulfonat + acetoacetat + NADP+ 2-(2-oksopropiltio)etansulfonat + CO2 + NADPH
Ovaj enzim takođe deluje na tioetre.
Reference уреди
- ^ Allen, J.R., Clark, D.D., Krum, J.G. and Ensign, S.A. (1999). „A role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylation”. Proc. Natl. Acad. Sci. USA. 96: 8432—8437. PMID 10411892.
- ^ Clark, D.D., Allen, J.R. and Ensign, S.A. (2000). „Characterization of five catalytic activities associated with the NADPH:2-ketopropyl-coenzyme M [2-(2-ketopropylthio)ethanesulfonate] oxidoreductase/carboxylase of the Xanthobacter strain Py2 epoxide carboxylase system”. Biochemistry. 39: 1294—1304. PMID 10684609.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- 2-oxopropyl-CoM+reductase+(carboxylating) на US National Library of Medicine Medical Subject Headings (MeSH)
