Anhidro-N-acetilmuraminska kiselina kinaza
(преусмерено са EC 2.7.1.170)
Anhidro-N-acetilmuraminska kiselina kinaza (EC 2.7.1.170, anhMurNAc kinaza, AnmK) je enzim sa sistematskim imenom ATP:1,6-anhidro-N-acetil-beta-muramat 6-fosfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Anhidro-N-acetilmuraminska kiselina kinaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.1.170 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ovaj enzim, zajedno sa EC 4.2.1.126, N-acetilmuraminska kiselina 6-fosfat eterazom, je neophodan za upotrebu anhidro-N-acetilmuraminske kiseline kod proteobakterija.
Reference
уреди- ^ Uehara, T., Suefuji, K., Valbuena, N., Meehan, B., Donegan, M. and Park, J.T. (2005). „Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine-phosphate”. J. Bacteriol. 187: 3643—3649. PMID 15901686.
- ^ Uehara, T., Suefuji, K., Jaeger, T., Mayer, C. and Park, J.T. (2006). „MurQ etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall”. J. Bacteriol. 188: 1660—1662. PMID 16452451.
- ^ Bacik, J.P., Whitworth, G.E., Stubbs, K.A., Yadav, A.K., Martin, D.R., Bailey-Elkin, B.A., Vocadlo, D.J. and Mark, B.L. (2011). „Molecular basis of 1,6-anhydro bond cleavage and phosphoryl transfer by Pseudomonas aeruginosa 1,6-anhydro-N-acetylmuramic acid kinase”. J. Biol. Chem. 286: 12283—12291. PMID 21288904.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Anhydro-N-acetylmuramic+acid+kinase на US National Library of Medicine Medical Subject Headings (MeSH)