Glikozilkeramidaza
(преусмерено са EC 3.2.1.62)
Glikozilkeramidaza (EC 3.2.1.62, florizinska hidrolaza, floretin-glukozidaza, glikozil keramidna glikozilhidrolaza, cerebrozidaza, floridzin beta-glukozidaza, laktaza-florizin hidrolaza, floridzin glukozidaza) je enzim sa sistematskim imenom glikozil-N-acilsfingozin glikohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glikozilkeramidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.62 | ||||||||
| CAS broj | 2605556 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim takođe hidrolizuje florizin do floretina i glukoze.
Reference уреди
- ^ Leese, H.J. & Semenza, G. (1973). „On the identity between the small intestinal enzymes phlorizin hydrolase and glycosylceramidase”. J. Biol. Chem. 248: 8170—8173. PMID 4752949.
- ^ Lorenz-Meyer, H., Blum, A.L., Haemmerli, H.P. and Semenza, G. (1972). „A second enzyme defect in acquired lactase deficiency: lack of small-intestinal phlorizin-hydrolase”. Eur. J. Clin. Invest. 2: 326—331. PMID 5082068.
- ^ Malathi, P. & Crane, R.K. (1969). „Phlorizin hydrolase: a β-glucosidase of hamster intestinal brush border membrane”. Biochim. Biophys. Acta. 173: 245—256. PMID 5774775.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Glycosylceramidase на US National Library of Medicine Medical Subject Headings (MeSH)
