Eksodezoksiribonukleaza III
Eksodezoksiribonukleaza III (EC 3.1.11.2, Escherichia coli eksonukleaza III, E. coli eksonukleaza III, endoribonukleaza III) je enzim sa sistematskim imenom '.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Eksodezoksiribonukleaza III | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.11.2 | ||||||||
| CAS broj | 9037-44-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- Eksonukleolitičko razlaganje u 3'- ka 5'- smeru čime se formiraju nukleozid 5'-fosfati
Ova enzim preferentno deluje na dvolačanu DNK.
Reference уреди
- ^ Lindahl, T., Gally, J.A. and Edelman, G.M. (1969). „Properties of deoxyribonuclease 3 from mammalian tissues”. J. Biol. Chem. 244: 5014—5019. PMID 5824576.
- ^ Richardson, C.C. & Kornberg, A. (1964). „A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. I. Purification of the enzyme and characterization of the phosphatase activity”. J. Biol. Chem. 239: 242—250. PMID 14114850.
- ^ Richardson, C.C., Lehman, I.R. and Kornberg, A. (1964). „A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. II. Characterization of the exonuclease activity”. J. Biol. Chem. 239: 251—258. PMID 14114851.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Exodeoxyribonuclease+III на US National Library of Medicine Medical Subject Headings (MeSH)
