Ektoinska sintaza
Ektoinska sintaza (EC 4.2.1.108, N-acetildiaminobutirat dehidrataza, N-acetildiaminobutanoat dehidrataza, L-ektoin sintaza, EctC, 4-N-acetil-L-2,4-diaminobutanoat hidrolijaza (formira L-ektoin)) je enzim sa sistematskim imenom N4-acetil-L-2,4-diaminobutanoat hidrolijaza (formira L-ektoin).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Ektoinska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.108 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- N4-acetil-L-2,4-diaminobutanoat L-ektoin + H2O
Ovaj enzim učestvuje u biosintezi ektoina.
Reference уреди
- ^ Peters, P., Galinski, E.A. and Truper, H.G. (1990). „The biosynthesis of ectoine”. FEMS Microbiol. Lett. 71: 157—162.
- ^ Ono, H., Sawada, K., Khunajakr, N., Tao, T., Yamamoto, M., Hiramoto, M., Shinmyo, A., Takano, M. and Murooka, Y. (1999). „Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata”. J. Bacteriol. 181: 91—99. PMID 9864317.
- ^ Kuhlmann, A.U. & Bremer, E. (2002). „Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp”. Appl. Environ. Microbiol. 68: 772—783. PMID 11823218.
- ^ Louis, P. & Galinski, E.A. (1997). „Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli”. Microbiology. 143: 1141—1149. PMID 9141677.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Ectoine+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
