Ent-kaurenska sintaza
Ent-kaurenska sintaza (EC 4.2.3.19, ent-kaurenska sintaza B, ent-kaurenska сintetaza B, ent-kopalil-difosfat difosfat-lijaza (ciklizacija)) je enzim sa sistematskim imenom ent-kopalil-difosfat difosfat-lijaza (ciklizacija, formira ent-kauren).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Ent-kaurenska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.19 | ||||||||
| CAS broj | 9055-64-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- ent-kopalil difosfat ent-kauren + difosfat
Ovaj enzim je deo bifunkcionalanog enzima koji učestvuje u biosintezi ent-kaurena.
Reference уреди
- ^ Fall, R.R., West, C.A. (1971). „Purification and properties of kaurene synthetase from Fusarium moniliforme”. J. Biol. Chem. 246: 6913—6928. PMID 4331199.
- ^ Yamaguchi, S., Saito, T., Abe, H., Yamane, H., Murofushi, N. and Kamiya, Y. (1996). „Molecular cloning and characterization of a cDNA encoding the gibberellin biosynthetic enzyme ent-kaurene synthase B from pumpkin (Cucurbita maxima L.)”. Plant J. 10: 203—213. PMID 8771778.
- ^ Kawaide, H., Imai, R., Sassa, T. and Kamiya, Y. (1997). „Ent-kaurene synthase from the fungus Phaeosphaeria sp. L487. cDNA isolation, characterization, and bacterial expression of a bifunctional diterpene cyclase in fungal gibberellin biosynthesis”. J. Biol. Chem. 272: 21706—21712. PMID 9268298.
- ^ Toyomasu, T., Kawaide, H., Ishizaki, A., Shinoda, S., Otsuka, M., Mitsuhashi, W. and Sassa, T. (2000). „Cloning of a full-length cDNA encoding ent-kaurene synthase from Gibberella fujikuroi: functional analysis of a bifunctional diterpene cyclase”. Biosci. Biotechnol. Biochem. 64: 660—664. PMID 10803977.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Ent-kaurene+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
