FMN adenililtransferaza
(преусмерено са FADS)
FMN adenililtransferaza (EC 2.7.7.2, FAD pirofosforilaza, riboflavin mononukleotid adenililtransferaza, adenozin trifosfat-riboflavin mononukleotid transadenilaza, adenozin trifosfat-riboflavin mononukleotid transadenilaza, riboflavin adenin dinukleotid pirofosforilaza, riboflavin adenin dinukleotid adenililtransferaza, flavin adenin dinukleotid sintetaza, FADS) je enzim sa sistematskim imenom ATP:FMN adenililtransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
FMN adenililtransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.7.2 | ||||||||
CAS broj | 9026-37-3 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Za rad ovog enzima je neophodan jon Mg2+. On je visoko specifičan za ATP kao donor fosfata.
Reference
уреди- ^ Giri, K.V., Rao, N.A., Cama, H.R. and Kumar, S.A. (1960). „Studies on flavinadenine dinucleotide-synthesizing enzyme in plants”. Biochem. J. 75: 381—386. PMID 13828163.
- ^ Schrecker, A.W. & Kornberg, A. (1950). „Reversible enzymatic synthesis of flavin-adenine dinucleotide”. J. Biol. Chem. 182: 795—803.
- ^ Sandoval, F.J. & Roje, S. (2005). „An FMN hydrolase is fused to a riboflavin kinase homolog in plants”. J. Biol. Chem. 280: 38337—38345. PMID 16183635.
- ^ Oka, M. & McCormick, D.B. (1987). „Complete purification and general characterization of FAD synthetase from rat liver”. J. Biol. Chem. 262: 7418—7422. PMID 3034893.
- ^ Brizio, C., Galluccio, M., Wait, R., Torchetti, E.M., Bafunno, V., Accardi, R., Gianazza, E., Indiveri, C. and Barile, M. (2006). „Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase”. Biochem. Biophys. Res. Commun. 344: 1008—1016. PMID 16643857.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- FAD+synthetase на US National Library of Medicine Medical Subject Headings (MeSH)