Fosfinotricin acetiltransferaza
Fosfinotricin acetiltransferaza (EC 2.3.1.183, PAT, PPT acetiltransferaza, Pt-N-acetiltransferaza, ac-Pt) je enzim sa sistematskim imenom acetil-KoA:fosfinotricin N-acetiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Fosfinotricin acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.183 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- acetil-KoA + fosfinotricin KoA + N-acetilfosfinotricin
Supstrat, fosfinotricin, se koristi kao neselektivni herbicid i potentni inhibitor enzima EC 6.3.1.2, glutamat---amonijak ligaze, koji je ključni enzim azotnog metabolizma kod biljki.
Reference уреди
- ^ Botterman, J., Gosselé, V., Thoen, C. and Lauwereys, M. (1991). „Characterization of phosphinothricin acetyltransferase and C-terminal enzymatically active fusion proteins”. Gene. 102: 33—37. PMID 1864506.
- ^ Dröge-Laser, W., Siemeling, U., Pühler, A. and Broer, I. (1994). „The metabolites of the herbicide L-phosphinothricin (glufosinate) (identification, stability, and mobility in transgenic, herbicide-resistant, and untransformed plants)”. Plant Physiol. 105: 159—166. PMID 12232195.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Phosphinothricin+acetyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
