Fosforibozilantranilatna izomeraza
(преусмерено са Fosforibozilantranilat izomeraza)
Fosforibozilantranilatna izomeraza (EC 5.3.1.24, PRA izomeraza, PRAI, IGPS:PRAI (indol-3-glicerol-fosfat sintetaza/N-5'-fosforibozilantranilat izomeraza kompleks), N-(5-fosfo-beta-D-ribozil)antranilat ketol-izomeraza) je enzim sa sistematskim imenom N-(5-fosfo-beta-D-ribozil)antranilat aldoza-ketoza-izomeraza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Fosforibozilantranilatna izomeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 5.3.1.24 | ||||||||
| CAS broj | 37259-82-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- N-(5-fosfo-beta-D-ribozil)antranilat 1-(2-karboksifenilamino)-1-dezoksi-D-ribuloza 5-fosfat
U pojedinim organizmima ovaj enzim je deo multifunkcionalnog proteina.
Reference уреди
- ^ Braus, G.H., Luger, K., Paravicini, G., Schmidheini, T., Kirschner, K. and Hütter, R. (1988). „The role of the TRP1 gene in yeast tryptophan biosynthesis”. J. Biol. Chem. 263: 7868—7875. PMID 3286643.
- ^ Creighton, T.E. & Yanofsky, C. (1970). „Chorismate to tryptophan (Escherichia coli) - anthranilate synthetase, PR transferase, PRA isomerase, InGP synthetase, tryptophan synthetase”. Methods Enzymol. 17A: 365—380.
- ^ Hütter, R., Niederberger, P. and DeMoss, J.A. (1986). „Tryptophan synthetic genes in eukaryotic microorganisms”. Annu. Rev. Microbiol. 40: 55—77. PMID 3535653.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Phosphoribosylanthranilate+isomerase на US National Library of Medicine Medical Subject Headings (MeSH)
