Galaktozilkeramid sulfotransferaza
Galaktozilkeramid sulfotransferaza (EC 2.8.2.11, GSase, 3'-fosfoadenozin-5'-fosfosulfat-cerebrozid sulfotransferaza, galaktocerebrozidna sulfotransferaza, galaktolipidna sulfotransferaza, glikolipidna sulfotransferaza, glikosfingolipidna sulfotransferaza) je enzim sa sistematskim imenom 3'-fosfoadenilil-sulfat:galaktozilkeramid 3'-sulfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Galaktozilkeramid sulfotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.8.2.11 | ||||||||
| CAS broj | 2622964 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 3'-fosfoadenilil sulfat + galaktozilkeramid adenozin 3',5'-bisfosfat + galaktozilkeramidsulfat
Ovaj enzim takođe deluje na laktozilkeramid.
Reference уреди
- ^ McKhann, G.M., Levy, R. and Ho, W. (1965). „Metabolism of sulfatides. I. The effect of galactocerebrosides on the synthesis of sulfatides”. Biochem. Biophys. Res. Commun. 20: 109—113. PMID 5850675.
- ^ Sakakibara, N., Gasa, S., Kamio, K., Makita, A. and Koyanagi, T. (1989). „Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma”. Cancer Res. 49: 335—339. PMID 2562926.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Galactosylceramide+sulfotransferase на US National Library of Medicine Medical Subject Headings (MeSH)
