Glicin dehidrogenaza (formira cijanid)
Glicin dehidrogenaza (formira cijanid) (EC 1.4.99.5, cijanovodonična sintaza, HCN sintaza) je enzim sa sistematskim imenom glicin:akceptor oksidoreduktaza (formira cijanovodonik).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glicin dehidrogenaza (formira cijanid) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.4.99.5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- glicin + 2 A hidrogen cijanid + CO2 + 2 AH2
Ova enzim iz Pseudomonas sp. sadrži FAD. On je vezan za membranu.
Reference
уреди- ^ Wissing, F. (1975). „Cyanide production from glycine by a homogenate from a Pseudomonas species”. J. Bacteriol. 121: 695—699. PMID 234422.
- ^ Castric, P.A. (1977). „Glycine metabolism by Pseudomonas aeruginosa: Hydrogen cyanide biosynthesis”. J. Bacteriol. 130: 826—831. PMID 233722.
- ^ Laville, J., Blumer, C., Von Schroetter, C., Gaia, V., Defago, G., Keel, C. and Haas, D. (1998). „Characterization of the hcnABC gene cluster encoding hydrogen cyanide synthase and anaerobic regulation by ANR in the strictly aerobic biocontrol agent Pseudomonas fluorescens CHA0”. J. Bacteriol. 180: 3187—3196. PMID 9620970.
- ^ Blumer, C. & Haas, D. (2000). „Mechanism, regulation, and ecological role of bacterial cyanide biosynthesis”. Arch. Microbiol. 173: 170—177. PMID 10763748.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Glycine+dehydrogenase+(cyanide-forming) на US National Library of Medicine Medical Subject Headings (MeSH)
