Glikosfingolipidna deacilaza
Glikosfingolipidna deacilaza (EC 3.5.1.69, glikosfingolipid keramidna deacilaza) je enzim sa sistematskim imenom glikosfingolipid amidohidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glikosfingolipidna deacilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.69 | ||||||||
| CAS broj | 122544-53-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Hidroliza gangliozida i neutralnih glikosfingolipida, čime se oslobađaju masne kiseline i formiraju lizo-derivati
Ovaj enzim ne deluje na sfingolipide, kao što je keramid.
Reference
уреди- ^ Hirabayashi, Y., Kimura, M., Matsumoto, M., Yamamoto, K., Kadowaki, S. and Tochikura, T. (1988). „A novel glycosphingolipid hydrolyzing enzyme, glycosphingolipid ceramide deacylase, which cleaves the linkage between the fatty acid and sphingosine base in glycosphingolipids”. J. Biochem. (Tokyo). 103: 1—4. PMID 3360750.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Glycosphingolipid+deacylase на US National Library of Medicine Medical Subject Headings (MeSH)
