Glukozil-3-fosfoglicerat sintaza
Glukozil-3-fosfoglicerat sintaza (EC 2.4.1.266, GpgS protein, GPG sintaza, glukozilfosfoglicerat sintaza) je enzim sa sistematskim imenom NDP-glukoza:3-fosfo-D-glicerat 2-alfa-D-glukoziltransferaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glukozil-3-fosfoglicerat sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.266 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- NDP-glukoza + 3-fosfo-D-glicerat NDP + 2-O-(alfa-D-glukopiranozil)-3-fosfo-D-glicerat
Ovaj enzim učestvuje u biosintezi 2-O-(alfa-D-glukopiranozil)-D-glicerata.
Reference уреди
- ^ Costa, J., Empadinhas, N. and da Costa, M.S. (2007). „Glucosylglycerate biosynthesis in the deepest lineage of the bacteria: characterization of the thermophilic proteins GpgS and GpgP from Persephonella marina”. J. Bacteriol. 189: 1648—1654. PMID 17189358.
- ^ Costa, J., Empadinhas, N., Goncalves, L., Lamosa, P., Santos, H. and da Costa, M.S. (2006). „Characterization of the biosynthetic pathway of glucosylglycerate in the archaeon Methanococcoides burtonii”. J. Bacteriol. 188: 1022—1030. PMID 16428406.
- ^ Empadinhas, N., Albuquerque, L., Mendes, V., Macedo-Ribeiro, S. and da Costa, M.S. (2008). „Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase”. FEMS Microbiol. Lett. 280: 195—202. PMID 18221489.
- ^ Pereira, P.J., Empadinhas, N., Albuquerque, L., Sa-Moura, B., da Costa, M.S. and Macedo-Ribeiro, S. (2008). „Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis”. PLoS One. 3: #e3748—e3748. PMID 19015727.
- ^ Gest, P., Kaur, D., Pham, H.T., van der Woerd, M., Hansen, E., Brennan, P.J., Jackson, M. and Guerin, M.E. (2008). „Preliminary crystallographic analysis of GpgS, a key glucosyltransferase involved in methylglucose lipopolysaccharide biosynthesis in Mycobacterium tuberculosis”. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64: 1121—1124. PMID 19052364.
- ^ Kaur, D., Pham, H., Larrouy-Maumus, G., Riviere, M., Vissa, V., Guerin, M.E., Puzo, G., Brennan, P.J. and Jackson, M. (2009). „Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria”. PLoS One. 4: #e544—e5447. PMID 19421329.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Glucosyl-3-phosphoglycerate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
