Himaza
Himaza (EC 3.4.21.39, skeletalna mišićna proteaza, kožna himotriptička proteinaza, mastocitna serinska proteinaza, himaza, skeletalna mišićna (SK) proteaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Himaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.21.39 | ||||||||
| CAS broj | 97501-92-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Preferentno odvajanje: Phe- > Tyr- > Trp- > Leu-
Ovaj enzim je izolovan iz mastocitnih granulea.
Reference
уреди- ^ Woodbury, R.G., Everitt, M. and Neurath, H. (1981). „Mast cell proteases”. Methods Enzymol. 80: 588—609. PMID 7043202.
- ^ Powers, J.C., Tanaka, T., Harper, J.W., Minematsu, Y., Barker, L., Lincoln, D., Crumley, K.V., Fraki, J.E., Schechter, N.M., Lazarus, G.G., Nakajima, K., Nakashino, K., Neurath, H. and Woodbury, R.G. (1985). „Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors”. Biochemistry. 24: 2048—2058. PMID 3893542.
- ^ Johnson, L.A., Moon, K.E. and Eisenberg, M. (1986). „Purification to homogeneity of the human skin chymotryptic proteinase "chymase"”. Anal. Biochem. 155: 358—364. PMID 2425663.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
