Hineloran

Hineloran je leki koji deluje kao selektivni dopaminski agonist za D₂ podtipe.^[1]^[2]^[3]

Hineloran
IUPAC ime

(5aR,9aR)-6-propil-5a,7,8,9,9a,10-heksahidro-5H-pirido[2,3-g]hinazolin-2-amin
Identifikatori
CAS broj	97548-97-5^Y
ATC kod	none
PubChem	CID 57242
UNII	Z0X4VT3Y1Q^Y
KEGG	D05677^Y
ChEMBL	CHEMBL155731^Y
Hemijski podaci
Formula	C₁₄H₂₂N₄
Molarna masa	246,350 g/mol
SMILES CCCN1CCC[C@H]2[C@H]1CC3=CN=C(N=C3C2)N

Reference

^ Caine SB, Negus SS, Mello NK, Patel S, Bristow L, Kulagowski J, Vallone D, Saiardi A, Borrelli E (2002). „Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists”. Journal of Neuroscience. 22 (7): 2977—88. PMID 11923462.
^ Gasior M, Paronis CA, Bergman J (2004). „Modification by dopaminergic drugs of choice behavior under concurrent schedules of intravenous saline and food delivery in monkeys”. The Journal of Pharmacology and Experimental Therapeutics. 308 (1): 249—59. PMID 14563783. doi:10.1124/jpet.103.052795.
^ Brooks JM, Sarter M, Bruno JP (2007). „D2-like receptors in nucleus accumbens negatively modulate acetylcholine release in prefrontal cortex”. Neuropharmacology. 53 (3): 455—63. PMC 2000917  . PMID 17681559. doi:10.1016/j.neuropharm.2007.06.006.

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Hinpirol

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