Hitin disaharidna deacetilaza
Hitin disaharidna deacetilaza (EC 3.5.1.105, hitobioza amidohidolaza, COD, hitin oligosaharidna deacetilaza, hitin oligosaharidna amidohidolaza) je enzim sa sistematskim imenom 2-(acetilamino)-4-O-(2-(acetilamino)-2-dezoksi-beta-D-glukopiranosil)-2-dezoksi-D-glukopiranoza acetilhidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Hitin disaharidna deacetilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.105 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2-(acetilamino)-4-O-[2-(acetilamino)-2-dezoksi-beta-D-glukopiranozil]-2-dezoksi-beta-D-glukopiranoza + H2O 2-(acetilamino)-4-O-(2-amino-2-dezoksi-beta-D-glukopiranozil)-2-dezoksi-beta-D-glukopiranoza + acetat
Ovaj enzim učestvuje u kataboličkoj kaskadi hitinolutičkih Vibrio vrsta.
Reference
уреди- ^ Kadokura, K., Rokutani, A., Yamamoto, M., Ikegami, T., Sugita, H., Itoi, S., Hakamata, W., Oku, T. and Nishio, T. (2007). „Purification and characterization of Vibrio parahaemolyticus extracellular chitinase and chitin oligosaccharide deacetylase involved in the production of heterodisaccharide from chitin”. Appl. Microbiol. Biotechnol. 75: 357—365. PMID 17334758.
- ^ Hirano, T., Kadokura, K., Ikegami, T., Shigeta, Y., Kumaki, Y., Hakamata, W., Oku, T. and Nishio, T. (2009). „Heterodisaccharide 4-O-(N-acetyl-β-D-glucosaminyl)-D-glucosamine is a specific inducer of chitinolytic enzyme production in Vibrios harboring chitin oligosaccharide deacetylase genes”. Glycobiology. 19: 1046—1053. PMID 19553519.
- ^ Ohishi, K., Yamagishi, M., Ohta, T., Motosugi, M., Izumida, H., Sano, H., Adachi, K., Miwa, T. (1997). „Purification and properties of two deacetylases produced by Vibrio alginolyticus H-8”. Biosci. Biotechnol. Biochem. 61: 1113—1117.
- ^ Ohishi, K., Murase, K., Ohta, T. and Etoh, H. (2000). „Cloning and sequencing of the deacetylase gene from Vibrio alginolyticus H-8”. J. Biosci. Bioeng. 90: 561—563. PMID 16232910.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Chitin+disaccharide+deacetylase на US National Library of Medicine Medical Subject Headings (MeSH)
