HycI peptidaza
HycI peptidaza (EC 3.4.23.51, HycI, HycE procesujući protein) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| HycI peptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.23.51 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Ovaj enzim specifično uklanja 32 aminokiseline dug peptid sa C-terminusa prekurzora velike podjedinice hidrogenaze 3 u Escherichia coli presecanjem C-terminalnog mesta na Arg537.
Za ovu reakciju je neophodno da je nikal vezan za prekurzor velike podjedinice hidrogenaze 3.
Reference уреди
- ^ Theodoratou, E., Paschos, A., Magalon, A., Fritsche, E., Huber, R. and Bock, A. (2000). „Nickel serves as a substrate recognition motif for the endopeptidase involved in hydrogenase maturation”. Eur. J. Biochem. 267: 1995—1999. PMID 10727938.
- ^ Yang, F., Hu, W., Xu, H., Li, C., Xia, B. and Jin, C. (2007). „Solution structure and backbone dynamics of an endopeptidase HycI from Escherichia coli: implications for mechanism of the [NiFe] hydrogenase maturation”. J. Biol. Chem. 282: 3856—3863. PMID 17150961.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- HycI+peptidase на US National Library of Medicine Medical Subject Headings (MeSH)
