Karikain
Karikain (EC 3.4.22.30, papajina peptidaza A, papajina peptidaza II, papajina proteinaza, papajina proteinaza III, papajina proteinaza 3, proteinaza omega, papajina proteinaza A, himopapain S, Pp) je enzim.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Karikain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.22.30 | ||||||||
| CAS broj | 39307-22-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Hidroliza proteina sa širokom specifičnošću za peptidne veze, slično dejstvu papaina i himopapaina
Ovaj enzim je izolovan iz papajinog ploda, Carica papaya.
Reference уреди
- ^ Schack, P. (1967). „Fractionation of proteolytic enzymes of dried papaya latex. Isolation and preliminary characterization of a new proteolytic enzyme”. C. R. Trav. Carlesberg. 36: 67—83. PMID 6043136.
- ^ Robinson, G.W. (1975). „Isolation and characterization of papaya peptidase A from commercial chymopapain”. Biochemistry. 16: 3695—3700. PMID 240390.
- ^ Polgár, L. (1984). „Problems of classification of papaya latex proteinases”. Biochem. J. 221: 555—556. PMID 6383350.
- ^ Brocklehurst, K., Salih, E., McKee, R. and Smith, H. (1985). „Fresh non-fruit latex of Carica papaya contains papain, multiple forms of chymopapain A and papaya proteinase”. Biochem. J. 228: 525—527. PMID 4015629.
- ^ Zucker, S., Buttle, D.J., Nicklin, M.J.H. and Barrett, A.J. (1985). „Proteolytic activities of papain, chymopapain and papaya proteinase III”. Biochim. Biophys. Acta. 828: 196—204. PMID 3919769.
- ^ Dubois, T., Kleinschmidt, T., Schnek, A.G., Looze, Y. and Braunitzer, G. (1988). „The thiol proteinases from the latex of Carica papaya L. II. The primary structure of proteinase”. Biol. Chem. Hoppe-Seyler. 369: 741—754. PMID 3063283.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
