Katepsin E (EC 3.4.23.34, proteinaza sporog kretanja, eritrocitna membranska aspartinska proteinaza, SMP, eritrocitna membranska aspartinska proteinaza, EMAP, nepepsinska proteinaza, katepsin D-slična kiselinska proteinaza, katepsinska E-slična kiselinska proteinaza, katepsinska D-tip proteinaza) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Katepsin E
Identifikatori
EC broj3.4.23.34
CAS broj110910-42-4
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
Aktivnost slična katepsinu D, sa malo širom specifičnošću

Ovaj enzim je prisutan u stomaku želucu, slezini i eritrocitnim membranama.

Reference

уреди
  1. ^ Lapresle, C., Puizdar, V., Porchon-Bertolotto, C., Joukoff, E. and Turk, V. (1986). „Structural differences between rabbit cathepsin E and cathepsin D”. Biol. Chem. Hoppe-Seyler. 367: 523—526. PMID 3741628. 
  2. ^ Yonezawa, S., Fujii, K., Maejima, Y., Tamoto, K., Mori, Y. and Muto, N. (1988). „Further studies on rat cathepsin E: subcellular localization and existence of the active subunit form”. Arch. Biochem. Biophys. 267: 176—183. PMID 3058036. 
  3. ^ Jupp, R.A., Richards, A.D., Kay, J., Dunn, B.M., Wyckoff, J.B., Samloff, I.M. and Yamamoto, K. (1988). „Identification of the aspartic proteinases from human erythrocyte membranes and gastric mucosa (slow-moving proteinase) as catalytically equivalent to cathepsin E”. Biochem. J. 254: 895—898. PMID 3058118. 
  4. ^ Azuma, T., Pals, G., Mohandas, T.K., Couvreur, J.M. and Taggart, R.T. (1989). „Human gastric cathepsin E. Predicted sequence, localization to chromosome 1, and sequence homology with other aspartic proteinases”. J. Biol. Chem. 264: 16748—16753. PMID 2674141. 

Literatura

уреди

Spoljašnje veze

уреди
  • Cathepsin+E на US National Library of Medicine Medical Subject Headings (MeSH)