Katepsin E
Katepsin E (EC 3.4.23.34, proteinaza sporog kretanja, eritrocitna membranska aspartinska proteinaza, SMP, eritrocitna membranska aspartinska proteinaza, EMAP, nepepsinska proteinaza, katepsin D-slična kiselinska proteinaza, katepsinska E-slična kiselinska proteinaza, katepsinska D-tip proteinaza) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Katepsin E | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.23.34 | ||||||||
| CAS broj | 110910-42-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Aktivnost slična katepsinu D, sa malo širom specifičnošću
Ovaj enzim je prisutan u stomaku želucu, slezini i eritrocitnim membranama.
Reference
уреди- ^ Lapresle, C., Puizdar, V., Porchon-Bertolotto, C., Joukoff, E. and Turk, V. (1986). „Structural differences between rabbit cathepsin E and cathepsin D”. Biol. Chem. Hoppe-Seyler. 367: 523—526. PMID 3741628.
- ^ Yonezawa, S., Fujii, K., Maejima, Y., Tamoto, K., Mori, Y. and Muto, N. (1988). „Further studies on rat cathepsin E: subcellular localization and existence of the active subunit form”. Arch. Biochem. Biophys. 267: 176—183. PMID 3058036.
- ^ Jupp, R.A., Richards, A.D., Kay, J., Dunn, B.M., Wyckoff, J.B., Samloff, I.M. and Yamamoto, K. (1988). „Identification of the aspartic proteinases from human erythrocyte membranes and gastric mucosa (slow-moving proteinase) as catalytically equivalent to cathepsin E”. Biochem. J. 254: 895—898. PMID 3058118.
- ^ Azuma, T., Pals, G., Mohandas, T.K., Couvreur, J.M. and Taggart, R.T. (1989). „Human gastric cathepsin E. Predicted sequence, localization to chromosome 1, and sequence homology with other aspartic proteinases”. J. Biol. Chem. 264: 16748—16753. PMID 2674141.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Cathepsin+E на US National Library of Medicine Medical Subject Headings (MeSH)
