Keramidaza
Keramidaza (EC 3.5.1.23, acilsfingozinska deacilaza, glikosfingolipidna keramidna deacilaza) je enzim sa sistematskim imenom N-acilsfingozin amidohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Keramidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.23 | ||||||||
| CAS broj | 37289-06-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- keramid + H2O karboksilat + sfingozin
Reference уреди
- ^ Nilsson, A. (1969). „The presence of spingomyelin- and ceramide-cleaving enzymes in the small intestinal tract”. Biochim. Biophys. Acta. 176: 339—347. PMID 5775951.
- ^ Yavin, E. & Gatt, S. (1969). „Enzymatic hydrolysis of sphingolipids. 8. Further purification and properties of rat brain ceramidase”. Biochemistry. 8: 1692—1698. PMID 5805303.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Ceramidase на US National Library of Medicine Medical Subject Headings (MeSH)
