Koenzim F420-1:gama-L-glutamat ligaza
Koenzim F420-1:gama-L-glutamat ligaza (EC 6.3.2.34, F420:gama-glutamil ligaza, CofE-AF, MJ0768, CofE) je enzim sa sistematskim imenom L-glutamat:koenzim F420-1 ligaza (formira GDP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Koenzim F420-1:gama-L-glutamat ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.2.34 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj protein katalizuje the sukcesivnu adiciju dva glutamatna ostatka na kofaktor F420 putem dve nezavisne reakcije.
Reference
уреди- ^ Li, H., Graupner, M., Xu, H. and White, R.H. (2003). „CofE catalyzes the addition of two glutamates to F420-0 in F420 coenzyme biosynthesis in Methanococcus jannaschii”. Biochemistry. 42: 9771—9778. PMID 12911320.
- ^ Nocek, B., Evdokimova, E., Proudfoot, M., Kudritska, M., Grochowski, L.L., White, R.H., Savchenko, A., Yakunin, A.F., Edwards, A. and Joachimiak, A. (2007). „Structure of an amide bond forming F420:γ-glutamyl ligase from Archaeoglobus fulgidus – a member of a new family of non-ribosomal peptide synthases”. J. Mol. Biol. 372: 456—469. PMID 17669425.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Coenzyme+F420-1:gamma-L-glutamate+ligase на US National Library of Medicine Medical Subject Headings (MeSH)
